A9736

A-438079 hydrochloride hydrate

≥98% (HPLC)

• Synonym(e): 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate
• Empirische Formel (Hill-System): C₁₃H₉Cl₂N₅·HCl · xH₂O
• CAS-Nummer: 899431-18-6
• Molekulargewicht: 342.61 (anhydrous basis)
• MDL-Nummer: MFCD17215929
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329771058
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: 20 mg/mL, clear
• Ersteller: Abbott
• Lagertemp.: 2-8°C
• SMILES String: O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3
• InChI: 1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2
• InChIKey: ZHFJJBAKSROKNO-UHFFFAOYSA-N

Beschreibung

Anwendung

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

Biochem./physiol. Wirkung

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Leistungsmerkmale und Vorteile

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable