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Merck

A9545

Sigma-Aldrich

4-Aminophenyl β-D-galactopyranoside

≥98% (TLC), β-galactosidase substrate

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About This Item

Empirische Formel (Hill-System):
C12H17NO6
CAS-Nummer:
Molekulargewicht:
271.27
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.25

Qualitätsniveau

Assay

≥98% (TLC)

Form

powder

Optische Aktivität

[α]/D -42.00 to -34.00°, c = 9.00-11.00 mg/mL in water

Methode(n)

thin layer chromatography (TLC): suitable

Farbe

white to yellow cast

Löslichkeit

water: 49.00-51.00 mg/mL, clear, colorless to yellow

Lagertemp.

−20°C

SMILES String

Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1

InChI

1S/C12H17NO6/c13-6-1-3-7(4-2-6)18-12-11(17)10(16)9(15)8(5-14)19-12/h1-4,8-12,14-17H,5,13H2

InChIKey

MIAKOEWBCMPCQR-UHFFFAOYSA-N

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Anwendung

4-Aminophenyl β-D-galactopyranoside (PAPG, 4-APG) is used as a substrate for the development of β-galactosidase(s) (GUS)-dependent assay systems via the formation of an electroactive product. It may be used to create affinity matricies for the capture or purification of β-galactosidase(s).

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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Ardhendu K Mandal et al.
Journal of drug targeting, 13(5), 305-315 (2005-10-04)
Rats were administered a single dose of plant origin phenolic antioxidant Quercetin (QC) in free, liposome encapsulated and galactosylated liposome encapsulated forms 2 h prior to hepatotoxic dose of carbontetrachloride (CCl4, 40% v/v in olive oil, 1 ml/kg b.wt). Among
M Naoi et al.
Journal of neurochemistry, 47(6), 1879-1884 (1986-12-01)
Using a synthesized glycoprotein, beta-galactosidase modified with p-aminophenyl beta-D-galactopyranoside (beta-D-Gal beta-gal), the incorporation of the glycoprotein into bovine brain synaptosomes was studied. The uptake was mediated by a specific receptor to beta-D-galactoside, and was inhibited by GM1 ganglioside. The uptake
Effect of membrane composition on the immune reactivity of galactosylated liposomes.
D P Sarkar et al.
Indian journal of biochemistry & biophysics, 21(3), 155-157 (1984-06-01)
Daniel Bello-Gil et al.
PloS one, 9(1), e87995-e87995 (2014-02-06)
We have developed a general method for the specific and reversible immobilization of proteins fused to the choline-binding module C-LytA on functionalized graphite electrodes. Graphite electrode surfaces were modified by diazonium chemistry to introduce carboxylic groups that were subsequently used
Ardhendu K Mandal et al.
The Journal of pharmacology and experimental therapeutics, 320(3), 994-1001 (2006-12-02)
Arsenic, the environmental metalloid toxicant, is known to induce oxidative damage to liver and produce hepatic fibrosis. The theme of our study was to optimize and evaluate the therapeutic efficacy of galactosylated liposomal flavonoidal antioxidant, quercetin (QC), in combating arsenic-induced

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