91211

Oxyresveratrol

≥97.0% (HPLC)

• Synonym(e): (E)-2,3′,4,5′-Stilbenetetrol, 2,3′,4,5′-Tetrahydroxy-trans-stilben, 4-[(1E)-2-(3,5-Dihydroxyphenyl)-ethenyl]-1,3-dihydroxybenzol
• Empirische Formel (Hill-System): C₁₄H₁₂O₄
• CAS-Nummer: 29700-22-9
• Molekulargewicht: 244.24
• MDL-Nummer: MFCD11974969
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329770004
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97.0% (HPLC)
• Form: solid
• Anwendung(en): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES String: Oc1ccc(\C=C\c2cc(O)cc(O)c2)c(O)c1
• InChI: 1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+
• InChIKey: PDHAOJSHSJQANO-OWOJBTEDSA-N

Beschreibung

Allgemeine Beschreibung

Oxyresveratrol (OXY or ORV) is a naturally occurring polyphenolic stilbene that is predominantly present in the heartwood of many plants. It is primarily extracted from Artocarpus lakoocha Roxb. plant, and is one of the main constituents of this plant. ORV has a very simple chemical structure with a trans-1,2-diphenylethylene in its core and two hydroxyls (OH) groups attached to each aromatic ring.

Anwendung

Oxyresveratrol has been used:

• with poly(lactic-co-glycolic acid) (PLGA) nanoparticles to test its antioxidant effects and to investigate its role in the inhibition of superoxide anion (O₂^-) generation
• to test its effects as an anti-neuroinflammatory agent on interleukin-1 beta (IL-1β)-induced HMC3 human microglial cell line
• as a reference standard to determine its existence in Artocarpus lakoocha Roxb. (AL) extract using high-performance liquid chromatography (HPLC)

Biochem./physiol. Wirkung

Oxyresveratrol is well-known due to its diverse biological and pharmacological properties. It is a potent antioxidant and anti-inflammatory agent. ORV also exerts neuroprotective activities and protects against cerebral ischemia, stroke, and several neurodegenerative disorders. It also displays anti-cancer, antimicrobial, hepatoprotective properties and protects against several other metabolic disorders. It is also a potent tyrosinase inhibitor.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H315,H318,H335
• P-Sätze: P280 - P302 + P352 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable