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15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

Synonym(e):

Piceid, Resveratrol 3-O-β-D-glucopyranosid, Resveratrol-3-β-mono-D-glucosid

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About This Item

Empirische Formel (Hill-System):
C20H22O8
CAS-Nummer:
65914-17-2
Molekulargewicht:
390.38
Beilstein:
54837
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329750984
NACRES:
NA.25

Assay

≥95% (HPLC)

Form

powder

Optische Aktivität

[α]1/D -66.0±2.0° in ethanol

Zusammensetzung

carbon, 60.5-62.5%

Lagertemp.

2-8°C

SMILES String

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

InChIKey

HSTZMXCBWJGKHG-AEGFYQLOSA-N

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Anwendung

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

Biochem./physiol. Wirkung

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
Hui Wen et al.
Biomedical microdevices, 14(4), 721-728 (2012-04-25)
Caenorhabditis elegans (C. elegans) is an excellent model organism for the study of aging and longevity. In this work, we presented a microfluidic approach for the evaluation of longevity in C. elegans under stress. The microfluidic device integrated multiple microvalves
M J Wu et al.
International journal of immunopathology and pharmacology, 25(4), 923-934 (2013-01-10)
Fulminant hepatic failure (FHF) is a devastating clinical syndrome with extremely poor prognosis and high mortality. Therefore, better treatment is urgently needed. Polydatin (PD), a traditional anti-inflammatory drug, has been described to protect against liver injury induced by certain hepatotoxins.
Giampietro Ravagnan et al.
Inflammation, 36(1), 26-34 (2012-09-08)
It is well known that human keratinocytes produce the anti-microbial peptide β-defensin 2. Its production is enhanced by pathogenic microorganisms or other environmental stressors. In this study, we evaluated the effect of resveratrol, a polyphenol found in several dietary source
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study
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