Y0000119

Hydroxycarbamid

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Hydroxyharnstoff, Hydroxycarbamid
• Lineare Formel: NH₂CONHOH
• CAS-Nummer: 127-07-1
• Molekulargewicht: 76.05
• Beilstein: 1741548
• MDL-Nummer: MFCD00007943
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329830855
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: hydroxycarbamide
• Hersteller/Markenname: EDQM
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: NC(=O)NO
• InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• InChIKey: VSNHCAURESNICA-UHFFFAOYSA-N
• Angaben zum Gen: human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Hydroxycarbamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Anti-neoplastisch. Inaktiviert die Ribonukleosid-Reduktase durch Bildung eines freien Nitroxid-Radikals, das ein freies Tyrosyl-Radikal im aktiven Zentrum des Enzyms bindet. Dadurch wird die Synthese von Desoxynukleotiden blockiert, was die DNA-Synthese hemmt und die Synchronisation oder den Zelltod in der S-Phase induziert.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H340,H361
• P-Sätze: P201 - P308 + P313
• Gefahreneinstufungen: Muta. 1B - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable