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PHR1152

Supelco

Schmelzpunktstandard für Phenylsalicylat

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Phenylsalicylat, Salol

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About This Item

Lineare Formel:
2-(HO)C6H4CO2C6H5
CAS-Nummer:
Molekulargewicht:
214.22
Beilstein:
393969
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to USP 1534209

API-Familie

phenyl salicylate

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

bp

172-173 °C/12 mmHg (lit.)

mp (Schmelzpunkt)

~Approximately 42 °C
41-43 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

Oc1ccccc1C(=O)Oc2ccccc2

InChI

1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H

InChIKey

ZQBAKBUEJOMQEX-UHFFFAOYSA-N

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Phenyl salicylate is a phenyl ester of salicylic acid and is used as a medicine under the name ′salol′ as an internal antiseptic. It finds its application in paints, waxes, and varnishes as it is found to absorb UV radiation in the range of 290-325 nm. It also shows its presence in cosmetics and sunscreens as a UV filter.

Anwendung

Phenyl salicylate may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7176 in the slot below. This is an example certificate only and may not be the lot that you receive.

Ähnliches Produkt

Piktogramme

Exclamation markEnvironment

Signalwort

Warning

Gefahreneinstufungen

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

230.0 °F - closed cup

Flammpunkt (°C)

110 °C - closed cup


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Selective synthesis of phenyl salicylate (salol) by esterification reaction over solid acid catalysts
Kuriakose G and Nagaraju N
J. Mol. Catal. A: Chem., 223(1-2), 155-159 (2004)
Chemical analysis and ecotoxicological effects of organic UV-absorbing compounds in aquatic ecosystems
Diaz-Cruz MS and Barcelo Damia
TrAC, Trends in Analytical Chemistry, 28(6), 708-717 (2009)
An examination of the thermodynamics of fusion, vaporization, and sublimation of several parabens by correlation gas chromatography
Umnahanant P and Chickos J
Journal of Pharmaceutical Sciences, 100(5), 1847-1855 (2011)
Simultaneous determination of the UV-filters benzyl salicylate, phenyl salicylate, octyl salicylate, homosalate, 3-(4-methylbenzylidene) camphor and 3-benzylidene camphor in human placental tissue by LC-MS/MS. Assessment of their in vitro endocrine activity
Jimenez-Diaz I, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 936(6), 80-87 (2013)
Use of 1H NMR to facilitate solubility measurement for drug discovery compounds
Lin M, et al.
International Journal of Pharmaceutics, 369(1-2), 47-52 (2009)

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