P5654

Piroxicam

≥98% (TLC)

• Synonym(e): 4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazin-1,1-dioxid
• Empirische Formel (Hill-System): C₁₅H₁₃N₃O₄S
• CAS-Nummer: 36322-90-4
• Molekulargewicht: 331.35
• EG-Nummer: 252-974-3
• MDL-Nummer: MFCD00057317
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278641
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 100
• Assay: ≥98% (TLC)
• Form: powder
• Lagertemp.: 2-8°C
• SMILES String: CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O
• InChI: 1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
• InChIKey: QYSPLQLAKJAUJT-UHFFFAOYSA-N
• Angaben zum Gen: human ... PTGS1(5742) , PTGS2(5743) ; rat ... Alox5(25290)

Beschreibung

Anwendung

Piroxicam has been used:

• for the induction of colitis in mice
• as a non-steroidal anti-inflammatory drug to increase the sensitivity to gut injury in interleukin-10 (IL-10) knockout mice
• as a chemopreventive agent and as a positive control to study its effects on tumor growth in mice small intestine

Biochem./physiol. Wirkung

Piroxicam is a non‐steroidal anti‐inflammatory drug (NSAID). It possesses analgesic properties and exhibits therapeutic effects against rheumatic disorders.

Cyclooxygenase-Inhibitor

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301 - H373
• P-Sätze: P260 - P264 - P270 - P301 + P310 - P314 - P405
• Gefahreneinstufungen: Acute Tox. 3 Oral - STOT RE 2 Oral
• Zielorgane: Gastrointestinal tract
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves