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Fenofibrinsäure

analytical standard

Synonym(e):

2-[4-(4-Chlorbenzoyl)phenoxy]-2-Methylpropionsäure, Fenofibrinsäure

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About This Item

Empirische Formel (Hill-System):
C17H15ClO4
CAS-Nummer:
42017-89-0
Molekulargewicht:
318.75
Beilstein:
2058973
EG-Nummer:
255-626-9
MDL-Nummer:
MFCD00792461
UNSPSC-Code:
77101502
PubChem Substanz-ID:
329769927
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥98.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Verunreinigungen

≤1.0% water

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2

InChI

1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)

InChIKey

MQOBSOSZFYZQOK-UHFFFAOYSA-N

Angaben zum Gen

human ... PPARA(5465)

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Anwendung

Fenofibric acid may be used as a reference standard in the determination of fenofibric acid in samples of human plasma using high performance liquid chromatography (HPLC) and liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H302 - H410

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCG5448
BCCC0735
BCBZ6721
BCBW7364
BCBQ9782V

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EPA 8270/Appendix IX Nitrosaminmischung certified reference material, 2000 μg/mL each component in methanol

Supelco

502138

EPA 8270/Appendix IX Nitrosaminmischung

Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LC?MS/MS with electrospray ionization: assay development, validation and application to a clinical study.
Trivedi K R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 39(3-4), 661-669 (2005)
Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography.
Masnatta D L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 687(2), 437-442 (1996)
Roger K Verbeeck et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(1), 61-67 (2015-04-17)
The therapeutic equivalence of multiple registered fenofibrate formulations, several of which are suprabioavailable and therefore marketed at lower dosage strengths than their reference products, is based on the results of bioequivalence studies. Most of these formulations show a higher bioavailability
Yunxia Lu et al.
Biochemical and biophysical research communications, 458(1), 1-7 (2015-01-17)
Fenofibrate (FF) is widely used to lower blood lipids in clinical practice, but whether its protective effect on endothelium-dependent vasodilatation (EDV) in thoracic aorta is related with endoplasmic reticulum (ER) stress remains unknown. In this study, female Sprauge Dawley rats
Martin J A Schackmann et al.
Biochimica et biophysica acta, 1851(2), 231-237 (2014-12-17)
X-linked adrenoleukodystrophy (X-ALD) is a neurometabolic disease that is caused by mutations in the ABCD1 gene. ABCD1 protein deficiency impairs peroxisomal very long-chain fatty acid (VLCFA) degradation resulting in increased cytosolic VLCFA-CoA levels, which are further elongated by the VLCFA-specific

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