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Merck

33490

Supelco

HMDI

analytical standard

Synonym(e):

4,4′-Methylen-bis-(cyclohexylisocyanat), 4,4′-Diisocyanato-methylendicyclohexan, 4,4′-HMDI, Bis-(4-isocyanatocyclohexyl)-methan

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About This Item

Lineare Formel:
CH2(C6H10NCO)2
CAS-Nummer:
Molekulargewicht:
262.35
Beilstein:
2217800
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard
mixture of isomers

Qualitätsniveau

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

environmental

Format

neat

SMILES String

O=C=NC1CCC(CC1)CC2CCC(CC2)N=C=O

InChI

1S/C15H22N2O2/c18-10-16-14-5-1-12(2-6-14)9-13-3-7-15(8-4-13)17-11-19/h12-15H,1-9H2

InChIKey

KORSJDCBLAPZEQ-UHFFFAOYSA-N

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Allgemeine Beschreibung

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flammpunkt (°F)

235.4 °F - closed cup

Flammpunkt (°C)

113 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

T-W Chuang et al.
Journal of biomedical materials research. Part A, 85(3), 722-730 (2007-09-28)
Poor compatibility between blood and metallic coronary artery stents is one reason for arterial restenosis. Immobilization of anticoagulant agents on the stent's surface is feasible for improving compatibility. We examined possible surface-coupling agents for anticoagulant agent immobilization. Hexamethylene diisocyanate (HMDI)
Extensive skin sensitization with minimal antibody production in guinea pigs as a result of exposure to dicyclohexylmethane-4,4'-diisocyanate.
M H Karol et al.
Toxicology and applied pharmacology, 65(2), 291-301 (1982-09-15)
[Intoxication due to dicyclohexyl-methane-4-4' diisocyanate exposure (author's transl)].
R Israeli et al.
International archives of occupational and environmental health, 48(2), 179-184 (1981-01-01)
Nasim Annabi et al.
Biomaterials, 30(27), 4550-4557 (2009-06-09)
In this study the feasibility of using high pressure CO2 to produce porous alpha-elastin hydrogels was investigated. Alpha-elastin was chemically crosslinked with hexamethylene diisocyanate that can react with various functional groups in elastin such as lysine, cysteine, and histidine. High
L H Chan-Chan et al.
Acta biomaterialia, 6(6), 2035-2044 (2009-12-17)
Biodegradable segmented polyurethanes (BSPUs) were prepared with poly(caprolactone) as a soft segment, 4,4'-methylene bis (cyclohexyl isocyanate) and either butanediol (BSPU1) or dithioerythritol (BSPU2) as a chain extender. BSPU samples were characterized in terms of their physicochemical properties and their hemocompatibility.

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