8.18586

Isophorondiisocyanat

(mixture of cis- and trans-isomers) for synthesis

• Synonym(e): Isophorondiisocyanat, 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcyclohexan, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexylisocyanat
• Empirische Formel (Hill-System): C₁₂H₁₈N₂O₂
• CAS-Nummer: 4098-71-9
• Molekulargewicht: 222.28
• MDL-Nummer: MFCD00064956
• UNSPSC-Code: 12352118
• EG-Index-Nummer: 223-861-6

Eigenschaften

• Dampfdruck: 0.0004 hPa ( 20 °C)
• Qualitätsniveau: 200
• Assay: ≥99.0% (GC)
• Form: liquid
• Selbstzündungstemp.: 430 °C
• Wirksamkeit: 4825 mg/kg LD₅₀, oral (Rat); >7000 mg/kg LD₅₀, skin (Rat)
• Expl.-Gr.: 0.7-4.5 % (v/v)
• bp: 158-159 °C/13 hPa
• mp (Schmelzpunkt): -60 °C
• Übergangstemp.: flash point 155 °C
• Löslichkeit: 0.015 g/L (slow decomposition)
• Dichte: 1.06 g/cm³ at 20 °C
• Lagertemp.: 2-30°C
• InChI: 1S/C12H18N2O2/c1-11(2)4-10(14-9-16)5-12(3,6-11)7-13-8-15/h10H,4-7H2,1-3H3
• InChIKey: NIMLQBUJDJZYEJ-UHFFFAOYSA-N

Beschreibung

Anwendung

• Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.: This study explores the development of thermoresponsive random poly(ether urethanes) synthesized using Isophorone diisocyanate. These polymers exhibit adjustable lower critical solution temperatures (LCSTs), making them suitable for controlled anticancer drug delivery applications. The research highlights the potential of Isophorone diisocyanate in creating advanced materials for medical use, specifically in drug delivery systems (Sardon et al., 2015).

Hinweis zur Analyse

Gehalt (GC, Flächen%): ≥ 99,0 % (a/a)
Dichte (d 20 °C/ 4 °C): 1,060 - 1,062
Identität (IR): entspricht

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H315 - H317 - H319 - H330 - H334 - H335 - H411
• P-Sätze: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Inhalation - Aquatic Chronic 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): 325.4 °F - closed cup
• Flammpunkt (°C): 163 °C - closed cup