07964

O-(2-Aminoethyl)-O′-methyl-polyethylenglykol

750

• Synonym(e): Aminopolyethylen-glycolmonomethylether, Methoxypolyethylenglycolamin
• Lineare Formel: H₂NCH₂CH₂(OCH₂CH₂)_nOCH₃
• CAS-Nummer: 80506-64-5
• MDL-Nummer: MFCD00131599
• UNSPSC-Code: 12162002
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Form: solid
• Farbe: white to yellow
• InChI: 1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
• InChIKey: ASUDFOJKTJLAIK-UHFFFAOYSA-N

Beschreibung

Anwendung

Methoxypolyethylene glycol amine can:

• Form dendritic micelles to enhance the solubility of hydrophobic compounds.
• Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
• Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.

Sonstige Hinweise

Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)