8.51014

Fmoc-OSu

≥99.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonym(e): FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)-succinimid, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
• Empirische Formel (Hill-System): C₁₉H₁₅NO₅
• CAS-Nummer: 82911-69-1
• Molekulargewicht: 337.33
• MDL-Nummer: MFCD00010733
• UNSPSC-Code: 12352108
• EG-Index-Nummer: 433-520-5
• NACRES: NA.22

Eigenschaften

• product name: Fmoc-OSu, Novabiochem^®
• Qualitätsniveau: 200
• Produktlinie: Novabiochem^®
• Assay: ≥99.0% (HPLC)
• Form: powder
• Hersteller/Markenname: Novabiochem^®
• mp (Schmelzpunkt): 145-148 °C
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Fmoc
• Lagertemp.: 2-8°C
• InChI: 1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2
• InChIKey: WMSUFWLPZLCIHP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Reagent for the preparation of pure Fmoc-amino acids that are free from contamination by Fmoc-dipeptides ^[1,2,3].

Literature references

^[1] A. Paquet (1982) Can. J. Chem., 60, 976.
^[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
^[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.

Anwendung

• Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion: This study uses Fmoc-OSu for selective functionalization of amines, demonstrating its role in synthesizing complex molecules with specific adhesive properties (Fischer et al., 2020).
• Fmoc-OASUD: A new reagent for the preparation of Fmoc-amino acids free from impurities resulting from Lossen rearrangement: Discusses the development of Fmoc-OASUD as a superior alternative to Fmoc-OSu, reducing impurities in peptide synthesis processes (Rao et al., 2016).

Verlinkung

Replaces: 01-63-0001

Hinweis zur Analyse

Farbe (visuell): weiß bis schwach gelb bis beige
Aussehen der Substanz (visuell): Pulver
Identität (IR): entspricht
Gehalt (HPLC, Fl.%): ≥ 99.0 % (a/a)
Löslichkeit (1 mmol in 2 ml DMF): klar löslich

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302 - H317 - H411
• P-Sätze: P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable