8.20610

Glyoxal

(40% solution in water) for synthesis

• UNSPSC-Code: 12352114
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 20.2 hPa ( 20 °C)
• Qualitätsniveau: 200
• Selbstzündungstemp.: 285 °C
• Wirksamkeit: 2000-5000 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH-Wert: 2-3 (20 °C in H₂O)
• bp: 104 °C/1013 hPa
• mp (Schmelzpunkt): -14 °C
• Dichte: 1.27 g/cm³ at 20 °C
• Lagertemp.: 2-30°C

Beschreibung

Anwendung

• HFIP-Mediated Multicomponent Reactions: Research demonstrates the use of HFIP (Hexafluoroisopropanol) in synthesizing pyrazole-linked thiazole derivatives, highlighting a new application in organic synthesis. Glyoxal is instrumental in the development of these multifunctional structures, contributing to advanced material design (Banerjee et al., 2024).


• Peptide Stapling in Protein Engineering: A study describes peptide stapling techniques using alpha-ketoaldehydes, which crosslink amines through glyoxal-modified linkers. This approach is pivotal in creating stable peptide structures for therapeutic applications (Guo et al., 2024).

Hinweis zur Analyse

Gehalt (acidimetrisch): 39.0 - 41.0 %
Dichte (d 20 °C/ 4 °C): 1.266 - 1.271

Sicherheitshinweise

• Piktogramme: GHS05,GHS07,GHS08
• Signalwort: Danger
• H-Sätze: H314 - H317 - H335 - H341
• P-Sätze: P202 - P261 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 1