481975

(--)-Nicotine, Ditartrate

Potent agonist of the nicotinic acetylcholine receptor.

• Synonym(e): (--)-Nicotine, Ditartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di- d-tartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di-d-tartrate
• Empirische Formel (Hill-System): C₁₀H₁₄N₂ · 2C₄H₆O₆
• CAS-Nummer: 65-31-6
• Molekulargewicht: 462.41
• UNSPSC-Code: 12352210
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Farbe: white to off-white
• Löslichkeit: ethanol: 10 mg/mL; water: 10 mg/mL
• Versandbedingung: ambient
• Lagertemp.: 10-30°C
• InChI: 1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1
• InChIKey: RFEJUZJILGIRHQ-WBPXWQEISA-N

Beschreibung

Allgemeine Beschreibung

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Nicotinic acetylcholine receptor

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Highly Toxic (H)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Rand, M.J. 1989. Prog. Brain Res. 79, 3.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H301,H319,H330,H361d,H411
• P-Sätze: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): 289.8 °F
• Flammpunkt (°C): 143.2 °C