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Key Documents

07-535

Sigma-Aldrich

Anti-MKP1 Antibody

Upstate®, from rabbit

Synonym(e):

Anti-CL100, Anti-HVH1, Anti-MKP-1, Anti-MKP1, Anti-PTPN10

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human, mouse

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... FARSB(10056)

Spezifität

Recognizes MKP1.

Immunogen

peptide corresponding to amino acids 87-101 (DERSAALDGAKRDGT-C) of human MAP kinase phosphatase 1 (MKP1)

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Kinasen & Phosphatasen
Detect MKP1 using this Anti-MKP1 Antibody validated for use in WB.

Qualität

routinely evaluated by immunoblot in RIPA lysates from 3T3/A31 cells

Zielbeschreibung

42 kDa

Physikalische Form

Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Lagerung und Haltbarkeit

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hinweis zur Analyse

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Modulation of gonadotropin-releasing hormone-induced extracellular signal-regulated kinase activation by dual-specificity protein phosphatase 1 in LbetaT2 gonadotropes.
Nguyen, KA; Intriago, RE; Upadhyay, HC; Santos, SJ; Webster, NJ; Lawson, MA
Endocrinology null
Akira Imasato et al.
The Journal of biological chemistry, 277(49), 47444-47450 (2002-10-03)
Despite the importance of glucocorticoids in suppressing immune and inflammatory responses, their role in enhancing host immune and defense response against invading bacteria is poorly understood. We have demonstrated recently that glucocorticoids synergistically enhance nontypeable Haemophilus influenzae (NTHi)-induced expression of
Shen-Hsi Yang et al.
PLoS genetics, 8(12), e1003112-e1003112 (2012-12-29)
Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interlinked transcriptional and signaling networks control the fate of these cells towards maintenance of pluripotency or differentiation. In this study we have focused
Marina Lasa et al.
Molecular and cellular biology, 22(22), 7802-7811 (2002-10-23)
The stress-activated protein kinase p38 stabilizes a number of mRNAs encoding inflammatory mediators, such as cyclooxygenase 2 (Cox-2). In HeLa cells the anti-inflammatory glucocorticoid dexamethasone destabilizes Cox-2 mRNA by inhibiting p38 function. Here we demonstrate that this effect is phosphatase
Epinephrine and AICAR-induced PGC-1? mRNA expression is intact in skeletal muscle from rats fed a high-fat diet.
Frier, BC; Wan, Z; Williams, DB; Stefanson, AL; Wright, DC
American Journal of Physiology. Cell Physiology null

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