857127P

17:0 Lyso PA

1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Synonym(e): heptadecanoyl lysophosphatidic acid; 1-heptadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(17:0/0:0); 17:0 LPA; 110679
• Empirische Formel (Hill-System): C₂₀H₄₀O₇PNa
• CAS-Nummer: 799268-66-9
• Molekulargewicht: 446.49
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Form: powder
• Verpackung: pkg of 1 × 25 mg (857127P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 857127P
• Lipid-Typ: phospholipids; cardiolipins
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100 nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.

Anwendung

17:0 Lyso PA is suitable to use as an internal standard:

• for mass spectrometric determination of lysophosphatidic acid molecular species in mouse peritoneal macrophages
• in the quantification of the lipid species released from extended synaptotagmin 2 (E-SYT2) expressed in mammalian cells by liquid chromatography with tandem mass spectrometry (LC-MS/MS)
• for the extraction of lipids from brain homogenate
• to extract lipids from the stomach washing solution for the determination of lysophosphatidic acid in a mouse stomach fluid

Biochem./physiol. Wirkung

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

Verpackung

5 mL Amber Glass Screw Cap Vial (857127P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available