857123P

16:0 Lyso PA

Avanti Polar Lipids

• Synonym(e): 1-hexadecanoyl-sn-glycero-3-phosphate (sodium salt); palmitoyl lysophosphatidic acid; PA(16:0/0:0); 16:0 LPA; 110678
• Empirische Formel (Hill-System): C₁₉H₃₈O₇PNa
• CAS-Nummer: 17618-08-5
• Molekulargewicht: 432.46
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Beschreibung: 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
• Assay: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Form: powder
• Verpackung: pkg of 1 × 200 mg (857123P-200mg); pkg of 1 × 25 mg (857123P-25mg)
• Hersteller/Markenname: Avanti Polar Lipids
• Lipid-Typ: phospholipids; cardiolipins
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Anwendung

16:0 Lyso PA is suitable to use as an internal standard to extract lipids from plasma sample of ovarian cancer patients. It is also suitable for the preparation of lipid solutions for synthesizing liposomes.

Biochem./physiol. Wirkung

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca²⁺ mobilization, neurotransmitter release and cell proliferation. Palmitoyl-lysophosphatidic acid helps in increasing aggregation, stimulated by adenosine diphosphate (ADP).

Verpackung

5 mL Amber Glass Screw Cap Vial (857123P-200mg)

5 mL Amber Glass Screw Cap Vial (857123P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids