850102P

16:0 Lyso PI

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

• Synonym(e): 1-hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/0:0; 110717
• Empirische Formel (Hill-System): C₂₅H₅₂NO₁₂P
• CAS-Nummer: 141553-69-7
• Molekulargewicht: 589.65
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• Form: powder
• Verpackung: pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug))
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 850102P
• Lipid-Typ: phosphoglycerides
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]
• InChIKey: RGTDHPZXKVTZBW-OGIGPNSJSA-N

Beschreibung

Allgemeine Beschreibung

Lysophosphatidylinositol (LPI) is a bioactive lipid.

Anwendung

16:0 Lyso PI (1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS) method conditions and also has been used as lysophosphatidylinositol (LPI) substrates in lysophosphatidylinositol acyltransferase biochemical assay to assay lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may also be used as synthetic LPI to compare its effect with LPI from liver in transferrin (Tf)mediated endocytosis.

Biochem./physiol. Wirkung

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium. LPI can serve as an autocrine regulator of cell growth, hence its known to participate in cancer progression. It can stimulate signaling cascades, that are essential for survival, migration and proliferation of cells.

Verpackung

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-500ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available