I9760

Jodessigsäure N-Hydroxysuccinimid-Ester

for peptide synthesis

• Synonym(e): N-Hydroxysuccinimide iodoacetate, N-Iodoacetoxysuccinimide
• Empirische Formel (Hill-System): C₆H₆INO₄
• CAS-Nummer: 39028-27-8
• Molekulargewicht: 283.02
• MDL-Nummer: MFCD00058451
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 57654310
• NACRES: NA.22

Eigenschaften

• product name: Jodessigsäure N-Hydroxysuccinimid-Ester, powder
• Form: powder
• Eignung der Reaktion: reagent type: cross-linking reagent
• Löslichkeit: DMF: 50 mg/mL
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: NHS ester
• Lagertemp.: −20°C
• SMILES String: O=C(N1OC(CI)=O)CCC1=O
• InChI: 1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
• InChIKey: VRDGQQTWSGDXCU-UHFFFAOYSA-N

Beschreibung

Anwendung

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 2-atom linker.

Vorsicht

The iodoacetyl group is light sensitive.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves