A59654

5-Aminoindol

97%

• Synonym(e): 5-Indolamin
• Empirische Formel (Hill-System): C₈H₈N₂
• CAS-Nummer: 5192-03-0
• Molekulargewicht: 132.16
• Beilstein: 112348
• EG-Nummer: 225-977-2
• MDL-Nummer: MFCD00005679
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24891044
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: crystals
• mp (Schmelzpunkt): 131-133 °C (dec.) (lit.)
• SMILES String: Nc1ccc2[nH]ccc2c1
• InChI: 1S/C8H8N2/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,9H2
• InChIKey: ZCBIFHNDZBSCEP-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for preparation of:

• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
• Cytotoxic and antimitotic agents
• Insulin-like growth factor 1 receptor inhibitors
• Antitumoral agents
• Factor Xa inhibitor
• Potential antivascular agents
• Gli1-mediated transcription in the Hedgehog pathway
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects
• PKCθ inhibitors
• HIV protease inhibitors

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H302,H311,H319,H400
• P-Sätze: P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves