925047

KB02-COOH

• Synonym(e): 2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid, Functionalized scout fragment
• Empirische Formel (Hill-System): C₁₃H₁₄ClNO₄
• CAS-Nummer: 2375196-30-6
• Molekulargewicht: 283.71
• NACRES: NA.22

Eigenschaften

• Eignung der Reaktion: reagent type: chemical modification reagent
• Qualitätsniveau: 100
• Lagertemp.: 2-8°C

Beschreibung

Anwendung

KB02-COOH is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131).

Related useful products may include cysteine fragment KB02 (912131), KB02-SLF (914738), IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059).

Technology spotlight: Proteomic Ligandability Assessment

Sonstige Hinweise

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable