544639

Methansulfonylaceton

97%

• Synonym(e): 1-(Methylsulfonyl)-2-propanon, NSC 35395
• Lineare Formel: CH₃C(O)CH₂SO₂CH₃
• CAS-Nummer: 5000-46-4
• Molekulargewicht: 136.17
• EG-Nummer: 225-665-6
• MDL-Nummer: MFCD00014745
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24878779
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: powder or crystals
• mp (Schmelzpunkt): 48-52 °C (lit.)
• Funktionelle Gruppe: ketone; sulfone
• SMILES String: CC(=O)CS(C)(=O)=O
• InChI: 1S/C4H8O3S/c1-4(5)3-8(2,6)7/h3H2,1-2H3
• InChIKey: NWEYGXQKFVGUFR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Methanesulfonylacetone is a sulfonyl group-containing active methylene compound. It can react with Baylis–Hillman acetates in dimethylformamide/potassium carbonate system to form ortho-hydroxyacetophenone derivatives.

Anwendung

Methanesulfonylacetone may be used in the preparation of 6-bromo-3-methanesulfonyl-2-methyl-quinolin-4-ol.

Reactant for:

• Stereoselective preparation of chiral cyclic ketones
• Preparation of poly-substituted pyridines
• Multicomponent cyclocondensation with aldehydes and aminoazoles
• Gold-catalyzed Friedlander cyclocondensation reaction
• Radical homoallylation reactions

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)