518379

Butylborsäure-N,N,N′,N′-tetramethyl-L-weinsäurediamidester

• Synonym(e): (4R,5R)-2-Butyl-N,N,N′,N′-tetramethyl-1,3,2-dioxaborolan-4,5-dicarboxamid
• Empirische Formel (Hill-System): C₁₂H₂₃BN₂O₄
• CAS-Nummer: 161344-85-0
• Molekulargewicht: 270.13
• MDL-Nummer: MFCD04113606
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24874017
• NACRES: NA.22

Eigenschaften

• Optische Aktivität: [α]20/D -105°, c = 1.7% in chloroform
• Qualitätsniveau: 100
• Brechungsindex: n20/D 1.478 (lit.)
• bp: 178-179 °C (lit.)
• Dichte: 1.072 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: amide
• SMILES String: CCCCB1O[C@H]([C@@H](O1)C(=O)N(C)C)C(=O)N(C)C
• InChI: 1S/C12H23BN2O4/c1-6-7-8-13-18-9(11(16)14(2)3)10(19-13)12(17)15(4)5/h9-10H,6-8H2,1-5H3/t9-,10-/m1/s1
• InChIKey: AFQWQRBBIZKYTE-NXEZZACHSA-N

Beschreibung

Anwendung

Butylboronic acid N,N,N′,N′-tetramethyl-L-tartaric acid diamide ester can be used as a cyclopropanation ligand in one of the key steps for the total synthesis of:

• (+)-Frondosin, a natural product from marine sponges.
• Marine cyanobacterium natural products: coibacins A and B.

Reactant for:
Preparation of biologically and pharmacologically active molecules

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)