445088

Mono-Ethylmalonat

• Synonym(e): (Ethoxycarbonyl)acetic acid, 3-Ethoxy-3-oxopropanoic acid, Ethyl hydrogen malonate, Ethyl malonate, Monoethyl hydrogen malonate
• Lineare Formel: HO₂CCH₂CO₂C₂H₅
• CAS-Nummer: 1071-46-1
• Molekulargewicht: 132.11
• EG-Nummer: 213-992-7
• MDL-Nummer: MFCD00020490
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24868159
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Verunreinigungen: <10% ethyl malonate, potassium salt
• Brechungsindex: n20/D 1.435 (lit.)
• bp: 106.5 °C/3 mmHg (lit.)
• Dichte: 1.119 g/mL at 25 °C (lit.)
• SMILES String: CCOC(=O)CC(O)=O
• InChI: 1S/C5H8O4/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3,(H,6,7)
• InChIKey: HGINADPHJQTSKN-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Preparation of tetramic acids via Dieckmann ring closure
• Organocatalytic decarboxylative Doebner-Knoevenagel reactions
• Conjugation to amino-modified oligonucleotides
• Acylation reactions (acylation agent)
• Indole glyoxylamides for potential Prion disease treatment
• Knoevenagel condensation with aldehydes

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter