417556

4-Fluorphenylborsäure

≥95%

• Synonym(e): 4-Fluor-benzolboronsäure
• Lineare Formel: FC₆H₄B(OH)₂
• CAS-Nummer: 1765-93-1
• Molekulargewicht: 139.92
• Beilstein: 2829653
• MDL-Nummer: MFCD00039136
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24866160
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95%
• Form: powder
• mp (Schmelzpunkt): 262-265 °C (lit.)
• SMILES String: OB(O)c1ccc(F)cc1
• InChI: 1S/C6H6BFO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
• InChIKey: LBUNNMJLXWQQBY-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Fluorophenylboronic acid can be used as a reactant in coupling reactions with arenediazonium tetrafluoroborates, iodonium salts, and iodanes. It is also used to make novel biologically active terphenyls.

It can also be used as a reactant in:

• Suzuki coupling using microwave and triton B catalyst.
• Pd-catalyzed direct arylation of pyrazoles with phenylboronic acids.
• Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles.
• Cu-catalyzed Petasis reactions.
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence.
• Ruthenium catalyzed direct arylation.
• Rh-catalyzed asymmetric conjugate additions.
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions.
• Suzuki cross-coupling of tetrabromothiophene.
• Palladium-catalyzed addition to nitriles.

Sonstige Hinweise

enthält schwankende Anteile von Anhydrid

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves