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P5669

Sigma-Aldrich

Pyridoxine

≥98%

Synonyme(s) :

Pyridoxol, Vitamin B6

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About This Item

Formule empirique (notation de Hill):
C8H11NO3
Numéro CAS:
65-23-6
Poids moléculaire :
169.18
Numéro CE :
200-603-0
Numéro MDL:
MFCD00006335
Code UNSPSC :
12352104
ID de substance PubChem :
24898690
Nomenclature NACRES :
NA.28

Pureté

≥98%

Forme

powder

Technique(s)

HPLC: suitable

Couleur

white to off-white

Pf

159-162 °C (lit.)

Chaîne SMILES 

Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3

Clé InChI

LXNHXLLTXMVWPM-UHFFFAOYSA-N

Informations sur le gène

human ... CYP1A2(1544)

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Catégories apparentées

Description générale

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.
Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B6 is distributed in nuts, whole grains and animal meat.

Application

Pyridoxine has been used as a component of:
  • artificial diet for sugarcane aphid pest
  • modified Strullu and Romand (MSR) medium for carrot root organ culture
  • Luria broth for E coli cultures

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.

Actions biochimiques/physiologiques

Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B6 leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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An artificial diet for the sugarcane aphid (Melanaphis sacchari Zehntner)(Hemiptera: Aphididae) with potential uses for in vitro toxicological studies
Toledo-Hernandez E, et al.
Florida entomologist, 101(3), 395-399 (2018)
Design, Validation, and Application of an Enzyme-Coupled Hydrogen Sulfide Detection Assay
Lynch MJ and Crane BR
Biochemistry, 58(6), 474-483 (2018)
Henrika Wickström et al.
AAPS PharmSciTech, 18(2), 293-302 (2016-10-16)
Printing technologies were recently introduced to the pharmaceutical field for manufacturing of drug delivery systems. Printing allows on demand manufacturing of flexible pharmaceutical doses in a personalized manner, which is critical for a successful and safe treatment of patient populations with
Tracking Lipid Transfer by Fatty Acid Isotopolog Profiling from Host Plants to Arbuscular Mycorrhiza Fungi
Redkar A, et al.
Bio-protocol, 8(7) (2018)
E B Rimm et al.
JAMA, 279(5), 359-364 (1998-02-12)
Hyperhomocysteinemia is caused by genetic and lifestyle influences, including low intakes of folate and vitamin B6. However, prospective data relating intake of these vitamins to risk of coronary heart disease (CHD) are not available. To examine intakes of folate and
Afficher tous les articles scientifiques apparentés

Protocoles

HPLC Analysis of Vitamins, Water Soluble on Discovery® C18

Separation of Pyridoxine; Nicotinamide; Nicotinic acid; Folic acid; (−)-Riboflavin, meets USP testing specifications; L-Ascorbic acid

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