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P9755

Sigma-Aldrich

Pyridoxine hydrochloride

≥98% (HPLC)

Synonyme(s) :

PN HCl, Pyridoxol hydrochloride

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About This Item

Formule empirique (notation de Hill):
C8H11NO3 · HCl
Numéro CAS:
Poids moléculaire :
205.64
Numéro Beilstein :
3632435
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352205
eCl@ss :
34058008
ID de substance PubChem :
Nomenclature NACRES :
NA.55

Niveau de qualité

Pureté

≥98% (HPLC)

Forme

powder

Technique(s)

HPLC: suitable

Couleur

white to off-white

Pf

214-215 °C (lit.)

Chaîne SMILES 

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

Clé InChI

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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Application

Pyridoxine hydrochloride has been used:
  • as a vitamin supplement in the basal medium for the cultivation of Bacillus mojavensis and Bacillus subtilis strains
  • as a supplement in pre-conditioning medium/MS salts to initiate somatic embryogenesis induction of Coffea canephora seeds
  • for oral administration in piglets to study its effect on the development of homocysteinemia

Actions biochimiques/physiologiques

Pyridoxine/Vitamin B6 plays a key role in the nervous, immune, and endocrine systems. It is also involved in the metabolic processes of proteins, lipids, and carbohydrates. Deficiency of pyridoxine may lead to convulsions and epileptic encephalopathy and result in infant abnormalities.

Pictogrammes

Corrosion

Mention d'avertissement

Danger

Mentions de danger

Conseils de prudence

Classification des risques

Eye Dam. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Marie-Édith Côté-Robitaille et al.
Journal of nutritional science, 4, e31-e31 (2015-10-27)
Homocysteine (Hcy) is an intermediary sulphur amino acid recognised for pro-oxidative properties in several species which may weaken immune competence in piglets. In this species, there is an acute 10-fold increase of concentrations of plasma Hcy (pHcy) during the first
Liat Ashkenazi-Hoffnung et al.
The Israel Medical Association journal : IMAJ, 15(1), 23-26 (2013-03-15)
Diclectin (pyridoxine 10 mg and doxylamine 10 mg) has traditionally been used to treat nausea and vomiting of pregnancy (NVP); however, this drug is unavailable in many countries. To evaluate the efficacy and safety of a simple bi-daily treatment regimen
Manfred Eggersdorfer et al.
Angewandte Chemie (International ed. in English), 51(52), 12960-12990 (2012-12-05)
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
Riccardo Montioli et al.
Human molecular genetics, 22(8), 1615-1624 (2013-01-17)
Dopa or aromatic amino acid decarboxylase (DDC, AADC) is a pyridoxal 5'-phosphate-dependent enzyme that catalyses the production of the neurotransmitters dopamine and serotonin. Among the so far identified mutations associated with AADC deficiency, an inherited rare neurometabolic disease, the S250F

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