D0184

2′-Deoxyuridine 5′-triphosphate sodium salt solution

100 mM in H₂O

• Synonyme(s) : dUTP sodium salt
• Formule empirique (notation de Hill): C₉H₁₅N₂O₁₄P₃ · xNa⁺
• Numéro CAS: 94736-09-1
• Poids moléculaire : 468.14 (free acid basis)
• Numéro MDL: MFCD01630759
• Code UNSPSC : 41106305
• ID de substance PubChem : 24893218
• Nomenclature NACRES : NA.52

Propriétés

• Pureté: ≥99%
• Forme: liquid
• Concentration: 100 mM in H₂O
• Couleur: colorless
• Activité étrangère: DNase, RNase, none detected
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
• Clé InChI: FVFWWPFKJNTHIQ-UHFFFAOYSA-N

Description

Description générale

2′-Deoxyuridine 5′-triphosphate (dUTP) is incorporated into DNA during DNA synthesis. It is one of the main intermediate during pyrimidine nucleotide biosynthesis. It is one of the sources of uracil in DNA. Deoxyuridine 5′-triphosphate nucleotidohydrolase suppresses the incorporation of dUTP into DNA. It converts dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP).

Application

2′-Deoxyuridine 5′-triphosphate sodium salt solution has been used in the mouse genomic DNA amplification by polymerase chain reaction (PCR). It is also suitable for conjunction with uracil DNA glycosylase to prevent carryover contamination in PCR. The dUTP is substituted for dTTP in the PCR reaction.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable