200100

Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside

≥98% (TLC), solid, O-linked glycosylation inhibitor, Calbiochem^®

• Synonyme(s) : Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside, Benzyl-α-GalNAc
• Formule empirique (notation de Hill): C₁₅H₂₁NO₆
• Numéro CAS: 3554-93-6
• Poids moléculaire : 311.33
• Numéro MDL: MFCD00057920
• Code UNSPSC : 12352200

Propriétés

• product name: Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside, Used as an inhibitor of O-linked glycosylation in a variety of cell lines.
• Niveau de qualité: 100
• Pureté: ≥98% (TLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: off-white
• Solubilité: hot ethanol: 1 mg/mL; DMSO: 100 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: CC(N[C@H]([C@H]([C@H]1O)O)[C@H](O[C@@H]1CO)OCC2=CC=CC=C2)=O
• InChI: 1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13+,14-,15+/m1/s1
• Clé InChI: SKOZFDIGKDPQBO-QMIVOQANSA-N

Description

Description générale

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. Also inhibits 2,3(O)-sialyltransferase and disrupts glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. It has also been used to inhibit 2,3(O)-sialyltransferase and disrupt glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
o-linked glycosylation

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Huet, G., et al. 1998. J. Cell Biol. 141, 1311.
Kuan, S.-F., et al. 1989. J. Biol. Chem. 264, 19271.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable