T4512

(±)-Taxifolin hydrate

≥90% (HPLC)

• Sinônimo(s): 3,3′,4′,5,7-Pentahydroxyflavanone hydrate, Dihydroquercetin hydrate
• Fórmula empírica (Notação de Hill): C₁₅H₁₂O₇ · xH₂O
• Número CAS: 24198-97-8
• Peso molecular: 304.25 (anhydrous basis)
• Número MDL: MFCD11044454
• Código UNSPSC: 12352200
• ID de substância PubChem: 24278739
• NACRES: NA.25

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥90% (HPLC)
• forma: powder
• solubilidade: DMSO: 20 mg/mL
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
• InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
• chave InChI: DNQPGSVMBPSRIR-LDXVYITESA-N
• Informações sobre genes: mouse ... Hexa(15211)

Descrição

Descrição geral

Taxifolin or dihydroquercetin is a naturally occurring secondary metabolic compound found in many plants such as onions, milk thistle, Douglas fir bark, and French maritime pine bark.

Aplicação

(±)-Taxifolin hydrate has been used to evaluate its effects when co-supplemented with trehalose to improve the quality of post-thawed ram semen. It may have been used as a reference standard to analyze the bioactive components of ethanolic extract of P. orientale (POE) using high-performance liquid chromatography (HPLC).

Ações bioquímicas/fisiológicas

(±)-Taxifolin exerts various pharmacological properties that include anti-inflammatory, anti-cancer, antiviral, and antimicrobial activities. It displays neuroprotective, hepatoprotective effects, and it also protects against cardiovascular diseases.

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P264 - P270 - P301 + P312 - P501
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves