SRP8044

CD40L, Soluble human

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• Sinônimo(s): ACRP30headless:CD154, ACRP30headless:CD40L, ACRP30headless:TNFSF5, ADIPOQ-CD40L
• Código UNSPSC: 12352200

Propriedades

• fonte biológica: human
• recombinante: expressed in CHO cells
• etiqueta: FLAG^® tagged
• Ensaio: >95% (SDS-PAGE)
• forma: lyophilized
• peso molecular: 35-40 kDa by SDS-PAGE
• embalagem: pkg of 10 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• Impurezas: <0.01 EU/μg endotoxin, tested
• nº de adesão UniProt: P29965
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... CD40LG(959)

Descrição

Descrição geral

CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.

Ações bioquímicas/fisiológicas

CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.

forma física

Lyophilized from PBS

Reconstituição

Reconstitute with 100 μL deionized water.

Outras notas

Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG^®-tag.

Informações legais

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable