SMB01061

Emetine

≥90% (LC/MS-ELSD)

• Sinônimo(s): (-)-Emetine
• Fórmula empírica (Notação de Hill): C₂₉H₄₀N₂O₄
• Número CAS: 483-18-1
• Peso molecular: 480.64
• Número MDL: MFCD00242944
• Código UNSPSC: 12352205
• NACRES: NA.25

Propriedades

• fonte biológica: plant
• Ensaio: ≥90% (LC/MS-ELSD)
• Formulário: solid
• peso molecular: 480.64
• solubilidade: water: soluble
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: N21[C@@H](C[C@@H]([C@H](C2)CC)C[C@H]4NCCc5c4cc(c(c5)OC)OC)c3c(cc(c(c3)OC)OC)CC1
• InChI: 1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1
• chave InChI: AUVVAXYIELKVAI-CKBKHPSWSA-N

Descrição

Descrição geral

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Aplicação

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Ações bioquímicas/fisiológicas

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.

Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Características e benefícios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Outras notas

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable