About This Item
Fórmula empírica (Notação de Hill):
C42H75N13O12
Peso molecular:
954.12
Código UNSPSC:
12352209
NACRES:
NA.32
Produtos recomendados
Ensaio
≥95% (HPLC)
forma
lyophilized
composição
Peptide Content, ≥70%
condição de armazenamento
protect from light
temperatura de armazenamento
−20°C
Amino Acid Sequence
Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Gly
Aplicação
Amyloid β (Aβ) refers to peptides derived from Amyloid precursor protein that vary in length from 36-43 amino acids. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport; function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress and mechanisms of protein cross-linking in the context of diseases such as Alzheimer′s disease and neurodegeneration.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Yan-Fang Xian et al.
Cellular and molecular neurobiology, 32(3), 353-360 (2011-11-02)
Beta-amyloid peptide (Aβ), a major protein component of senile plaques, has been considered as a critical cause in the pathogenesis of Alzheimer's disease (AD). Modulation of the Aβ-induced neurotoxicity has emerged as a possible therapeutic approach to ameliorate the onset
Houttuyniae Herba protects rat primary cortical cells from Aμ25-35-induced neurotoxicity via regulation of calcium influx and mitochondria-mediated apoptosis.
Park H, Oh MS.
Human & Experimental Toxicology (2012)
L Millucci et al.
Current protein & peptide science, 11(1), 54-67 (2010-03-06)
Amyloid-beta (Abeta) peptide is commonly found in human Alzheimer's disease (AD) brain and is the main component of Alzheimer amyloid plaques. The predominant forms of Abeta in the human brain are Abeta(1-40) and Abeta(1-42), but Abeta(25-35) fragment, physiologically present in
Min Young Um et al.
Neurochemical research, 37(4), 689-699 (2011-12-08)
We have investigated the neuroprotective effect of sesaminol glucosides (SG) in SK-N-SH cells. SG prevented apoptotic cell death induced by Aβ₂₅₋₃₅. In parallel, SK-N-SH cells exposed to Aβ₂₅₋₃₅ underwent oxidative stress as shown by the elevated level of intracellular ROS
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