SAB5700329

Anti-Phospho-γH2A.X-S139 antibody produced in rabbit

• Sinônimo(s): γH2AX, H2A.X, H2A/X, H2AFX, H2AX, Histone H2AX, gamma H2A.X, histone H2AX
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 15
• reatividade de espécies: rat, mouse, human
• concentração: 0.34 mg/ml
• técnica(s): immunofluorescence: 1:50-1:100; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão UniProt: P16104
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer139)
• Informações sobre genes: human ... H2AFX(3014)

Descrição

Descrição geral

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Imunogênio

A synthetic phosphorylated peptide around S139 of human γH2A.X (NP_002096.1).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20°C. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable