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Key Documents

SAB5300225

Sigma-Aldrich

Monoclonal Anti-PIK3CA antibody produced in mouse

clone 4F3, purified immunoglobulin, buffered aqueous solution

Sinônimo(s):

PI3K, p110-alpha

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

fonte biológica

mouse

conjugado

unconjugated

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

4F3, monoclonal

forma

buffered aqueous solution

peso molecular

124 kDa

reatividade de espécies

human

técnica(s)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000

Isotipo

IgG1

nº de adesão NCBI

NM_006218.2

nº de adesão UniProt

P42336

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... PIK3CA(5290)

Imunogênio

Purified recombinant fragment of human PIK3CA expressed in E.coli.
Mouse monoclonal antibody raised against PIK3CA

forma física

Purified antibody in PBS with 0.05% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Human molecular genetics, 23(21), 5649-5658 (2014-06-12)
Leucine-rich repeat kinase 2 (LRRK2) is a complex kinase and mutations in LRRK2 are perhaps the most common genetic cause of Parkinson's disease (PD). However, the identification of the normal physiological function of LRRK2 remains elusive. Here, we show that
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Endothelin-1 (ET-1)/endothelin A receptor (ETAR) signaling is important for osteosarcoma (OS) progression. Monoclonal antibodies (mAbs) targeting ganglioside GD2 reportedly inhibit tumor cell viability independent of the immune system. A recent study suggests that ganglioside GD2 may play an important role
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