SAB4504551

Anti-phospho-Synuclein-α (pTyr¹³³) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: ELISA; WB
• reatividade de espécies: mouse, human, rat
• técnica(s): ELISA: 1:40000; western blot: 1:500-1:1000
• citations: 3

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 14 kDa
• reatividade de espécies: mouse, human, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; western blot: 1:500-1:1000
• nº de adesão NCBI: P37840
• nº de adesão UniProt: P37840
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr133)
• Informações sobre genes: human ... SNCA(6622)

Descrição

Descrição geral

The SNCA (synuclein α) gene codes for a 140-amino acid protein a-synuclein, that is mapped to human chromosome 4q21-23.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Tyr133.

Immunogen Range: 91-140

Ações bioquímicas/fisiológicas

Synuclein-α is known to induce oligodendrocyte maturation. Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Mutations in the SNCA gene results in Parkinson′s disease.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable