SAB4504019

Anti-phospho-ALK (pTyr¹⁶⁰⁴) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-ALK1, Anti-CD246, Anti-NBLST3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 176 kDa
• reatividade de espécies: rat, human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: Q9UM73
• nº de adesão UniProt: Q9UM73
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr1604)
• Informações sobre genes: human ... ALK(238)

Descrição

Descrição geral

The anaplastic lymphoma kinase (ALK) gene codes for a transmembrane receptor tyrosine kinase (RTK) that has 1620 amino acids. It is a member of the insulin receptor superfamily and is usually expressed in nerve cells. ALK gene is mapped to human chromosome 2p23.2.

Imunogênio

The antiserum was produced against synthesized peptide derived from human ALK around the phosphorylation site of Tyr1604.

Immunogen Range: 1570-1619

Ações bioquímicas/fisiológicas

Anaplastic lymphoma kinase (ALK) has the ability to trigger Stat3 (signal transducer and activator of transcription 3) and rescue hematopoietic cells from cell death.Mutations in ALK-1 result in hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant disorder of localized angiodysplasia.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable