SAB4503132

Anti-FZD5 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): FZD5, Frizzled-5, Fz-5, FzE5, hFz5
• Código UNSPSC: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: ELISA; IF; IHC
• reatividade de espécies: mouse, human, rat
• técnica(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• citations: 6

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 64 kDa
• reatividade de espécies: mouse, human, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• nº de adesão NCBI: Q13467
• nº de adesão UniProt: Q13467
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... FZD5(7855)

Descrição

Descrição geral

Anti-FZD5 Antibody detects endogenous levels of total FZD5 protein.

The FZD5 (frizzled class receptor 5) gene encodes a receptor FZ5 for Wnt proteins and is mapped to human chromosome 2q33.3.

Imunogênio

The antiserum was produced against synthesized peptide derived from human FZD5.

Immunogen Range: 31-80

Ações bioquímicas/fisiológicas

Fzd5 (frizzled class receptor 5) is a receptor component for the canonical and non-canonical Wnt signaling pathways which is necessary for cell proliferation and cell differentiation. Fzd5 might serve as an important biomarker for eye malformation. The Wnt5a-Fz5 complex is known to support the functions of innate immunity. Fzd5 along with Gcm1 (chorion-specific transcription factor) is involved in a feedback mechanism that regulates trophoblast differentiation and chorionic branching in placenta.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable