SAB4502829

Anti-α-Synuclein (SNCA) Antibody

rabbit polyclonal

• Sinônimo(s): α-synuclein, NACP, Non-A β component of AD amyloid, Non-A4 component of amyloid precursor, SNCA
• Número MDL: MFCD02095740
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• Nome do produto: Anti-Synuclein-α antibody produced in rabbit, affinity isolated antibody
• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 14 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; western blot: 1:500-1:1000
• nº de adesão NCBI: P37840
• nº de adesão UniProt: P37840
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SNCA(6622)

Descrição

Descrição geral

Anti-Synuclein-α antibody detects endogenous levels of total Synuclein-α protein.

The SNCA (synuclein α) gene is mapped to human chromosome 4q22.1.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Synuclein-alpha.

Immunogen Range: 86-135

Ações bioquímicas/fisiológicas

Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Synuclein-α is known to induce oligodendrocyte maturation. The encoded protein is considered to be an important aggregate of Lewy bodies, contributing to the pathogenesis of Parkinson disease.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable