SAB4200566

Anti-KHSRP antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Sinônimo(s): Anti-FBP2, Anti-FUBP2, Anti-KH-type splicing regulatory protein, Anti-KSRP, Anti-MGC99676
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen ~82 kDa
• reatividade de espécies: rat, mouse, human
• concentração: ~1.0 mg/mL
• técnica(s): immunoprecipitation (IP): 1-2 μg using lysates of human HEK-293T cells; western blot: 0.25-0.50 μg/mL using whole extracts of mouse NIH-3T3 cells
• nº de adesão UniProt: Q92945
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KHSRP(8570) ; mouse ... Khsrp(16549) ; rat ... Khsrp(171137)

Descrição

Descrição geral

K-homology type-splicing regulatory protein (KHSRP) is a multifunctional RNA-binding protein. It contains four K homology RNA-binding domains and an unusual C-terminal domain. KHSRP is localized in neural and non-neural cell lines. It is located on the human chromosome at 19p13.3.

Especificidade

Anti-KHSRP recognizes human, mouse and rat KHSRP.

Imunogênio

synthetic peptide corresponding to an internal region of human KHSRP (GeneID: 8570), conjugated to KLH. The corresponding sequence is identical in rat, mouse, monkey, pig and dog KHSPR.

Aplicação

Anti-KHSRP antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.

Ações bioquímicas/fisiológicas

K-homology type-splicing regulatory protein (KHSRP) is involved in several cellular processes such as transcription, mRNA localization and alternative pre-mRNA splicing. It is also involved in mRNA decay and microRNA precursor maturation.

forma física

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Armazenamento e estabilidade

For continuous use, store at 2-8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable