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SAB4200216

Sigma-Aldrich

Monoclonal Anti-Caveolin-1 antibody produced in mouse

enhanced validation

clone CAV1, tissue culture supernatant

Sinônimo(s):

Anti-BSCL3, Anti-CAV1, Anti-CGL3, Anti-MSTP085, Anti-VIP21, Anti-caveolae protein, 22kDa

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About This Item

Número MDL:
MFCD01633097
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

mouse

conjugado

unconjugated

forma do anticorpo

tissue culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

CAV1, monoclonal

Formulário

buffered aqueous solution

peso molecular

antigen 22 kDa

reatividade de espécies

rat, human, mouse

validação aprimorada

independent
Learn more about Antibody Enhanced Validation

técnica(s)

immunohistochemistry: suitable
indirect immunofluorescence: 1:1000-1:2000 using human HUVEC or mouse 3T3 cells.
western blot: suitable

Isotipo

IgM

nº de adesão UniProt

Q03135

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CAV1(857)
mouse ... Cav1(12389)
rat ... Cav1(25404)

Categorias relacionadas

Descrição geral

Caveolin-1 (CAV1) is a multifunctional scaffolding protein, that has three exons. It is located on human chromosome 7q31.

Imunogênio

synthetic peptide corresponding to a sequence at the N-terminal of human caveolin-1, conjugated to KLH.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Monoclonal Anti-Caveolin-1 antibody has been used in western blot analysis.

Ações bioquímicas/fisiológicas

Caveolin-1 may play a major role in the growth and evolution of cancer. It participates in glucose metabolism. It may also participate in angiogenesis. Cav-1 helps to control the expression of glucose transporters.

forma física

Culture supernatant solution containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
068M4861V
22180216
036M4873V
024M4794V
083M4819

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Wu Y, et al.
PLoS ONE, 10(8), e0136671-e0136671 (2015)
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P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously
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Hyaluronan (HA) promotes transforming growth factor (TGF)-β1-driven myofibroblast phenotype. However, HA can also have disease-limiting activity. Bone morphogenetic protein-7 (BMP7) is an antifibrotic cytokine that antagonizes TGF-β1, and isolated studies have demonstrated that HA can both mediate and modulate BMP7
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The lymphatic system is a common avenue for the spread of breast cancer cells and dissemination through it occurs at least as frequently as hematogenous metastasis. Approximately 75% of primary breast cancers are estrogen receptor (ER) positive and the majority
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Global Trade Item Number

SKUGTIN
SAB4200216-200UL4061838035394
SAB4200216-25UL

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