SAB3500873

Monoclonal Anti-HEMAGGLUTININ antibody produced in mouse

clone 7B9B2, affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: 7B9B2, monoclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: virus
• concentração: 1 mg/mL
• técnica(s): ELISA: suitable; immunoblotting: suitable
• nº de adesão NCBI: AAT76166
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified

Descrição

Descrição geral

Hemagglutinin [Influenza A virus (A/chicken/Jilin/9/ 2004(H5N1))] is the principal surface antigen of influenza A virus. Hemagglutinin (HA) is a homotrimer; each monomer is a single polypeptide (HA0) that is post transcriptionally cleaved by host proteases into two subunits (HA1 and HA2). HA2 is highly conserved across different strains of influenza virus. HA preferentially binds to α2-3 sialic acid receptor in aves, whereas in human it binds to α2-6 sialic acid receptor.

Imunogênio

Antibody was raised against a peptide corresponding to 13 amino acids in the middle of the Hemagglutinin protein.

Ações bioquímicas/fisiológicas

Hemagglutinin (HA), specially HA2 is responsible for the binding of the virus to host receptors and enables its entry into the host cell through endocytosis through endosomal membrane fusion. HA is the primary target for neutralizing antibodies. HA is a potent target for drug and vaccine development.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable