SAB2501514

Anti-KLHL6 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-FLJ00029, Anti-kelch-like 6, Kelch-like 6 (Drosophila), Kelch-like protein KLHL6
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: goat
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: rat, canine, human, mouse
• técnica(s): indirect ELISA: suitable; western blot: suitable
• nº de adesão UniProt: Q8WZ60
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KLHL6(89857)

Descrição

Descrição geral

Kelch-like protein 6 (KLHL6) is a member of BTB (broad-complex, tramtrack and bric à brac)-kelch protein family. The gene encoding this protein is mapped to human chromosome 3q27. The encoded protein expression is confined to lymphoid tissue. KLHL6 exhibits high activity within the germinal center of B cells. The protein structure consists of a BTB domain at N terminal and six kelch repeats at the C terminal. KLHL6 protein is primarily expressed in human tonsil B lymphocytes.

Kelch-like protein 6 (KLHL6) plays a vital role in B-cell receptor (BCR) cell signaling and differentiation pathway of germinal center within B- cells. Aberration in the expression of this protein leads to chronic lymphocytic leukemia (CLL).

Imunogênio

Peptide with sequence SERTKPRMHEFQSE, from the internal region of the protein sequence according to NP_569713.2

Características e benefícios

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forma física

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable