SAB2500747
Anti-Pancreatic polypeptide/PPY antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Sinônimo(s):
Anti-HGNC:9327, Anti-PNP
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
goat
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
forma
buffered aqueous solution
reatividade de espécies
human
técnica(s)
immunohistochemistry: suitable
indirect ELISA: suitable
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... PPY(5539)
Categorias relacionadas
Descrição geral
Pancreatic polypeptide (PPY) or PP is an endogenous peptide hormone. It is secreted by the PP cells of the Islets of Langerhans, in the pancreas. PPY is part of the neuropeptide Y family of hormones. It is a 36 amino acid proteinand the gene encoding it is localized on human chromosome 17q21.31.
Imunogênio
Peptide with sequence C-TRPRYGKRHKEDT from the internal region of the protein sequence according to NP_002713.1.
Aplicação
Anti-Pancreatic polypeptide/PPY antibody produced in goat has been used in immunohistochemistry and immunofluorescence.
Ações bioquímicas/fisiológicas
Pancreatic polypeptide (PPY) or PP has glucoregulatory functions. It modulates biliary secretion and food digestion by preventing gastric emptying. PPY binds to the Y4 receptor and has a role in increasing the number of insulin receptors on hepatocytes. The protein has been associated with chronic pancreatitis and pancreatogenic diabetes. PPY also negatively regulates the expression of resistin hormone.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Hirohumi Suzuki et al.
Acta histochemica et cytochemica, 48(6), 173-178 (2016-02-09)
Immunohistochemical techniques were employed to investigate the distribution of the chemokine CXCL14, in the mouse pancreas. CXCL14-immunoreactive cells were detected in the peripheral region of the pancreatic islets and were immunoreactive for somatostatin, but not for glucagon, insulin, and pancreatic
Pancreatic polypeptide is involved in the regulation of body weight in pima Indian male subjects.
Diabetes (2004)
CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas
Hirohumi Suzuki, Toshiharu Yamamoto
Acta Histochemica Et Cytochemica (2015)
Immunohistochemical analysis of pancreatic islets of platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus ssp.)
Chuan He, et al.
Journal of Anatomy (2015)
Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding.
Lerch M, et al.
Biochemistry (2005)
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