RAB0849

Mouse Tnfsf10 / Tumor Necrosis Factor Ligand Superfamily Member 10 ELISA Kit

for serum, plasma and cell culture supernatants

• Código UNSPSC: 41116158
• NACRES: NA.32

Propriedades

• reatividade de espécies: mouse
• embalagem: kit of 96 wells (12 strips x 8 wells)
• técnica(s): ELISA: suitable
• entrada: sample type plasma; sample type serum; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 2 pg/mL; standard curve range: 2.46-600 pg/mL
• método de detecção: colorimetric
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: mouse ... Tnfsf10(22035)

Descrição

Descrição geral

The antibody pair provided in this kit recognizes mouse TRAIL/TNFSF10.

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Ações bioquímicas/fisiológicas

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates the extrinsic apoptotic pathway by binding death receptors (DR)-4 and 5. In addition to DR 4 and 5, TRAIL activates several other receptors such as decoy receptor (DcR)1, DcR2 and a soluble receptor called osteoprotegerin. TRAIL plays a vital role in the inhibition of autoimmune inflammation and cell cycle progression. TRAIL selectively kills tumor cells without damaging normal tissues and therefore, it might act as a tumor-selective anticancer agent. TRAIL-induced apoptosis is involved in various cellular processes including activation-induced cell death, homeostasis, intrathymic negative selection, autoimmunity suppression, and immune surveillance. Repeated dosage of recombinant soluble TRAIL triggers apoptosis, inhibits tumor progression, and increases viability of mice suffering from cancer.

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABWASH4 20X Wash Buffer (Item B)

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Warning
• Frases de perigo: H290
• Declarações de precaução: P234 - P390
• Classificações de perigo: Met. Corr. 1
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable