RAB0283
Human IL-1ra ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.84
Produtos recomendados
reatividade de espécies
human
embalagem
kit of 96 wells (12 strips x 8 wells)
técnica(s)
ELISA: suitable
capture ELISA: suitable
entrada
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 100 pg/mL
standard curve range: 0.124-30 ng/mL
método de detecção
colorimetric
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IL1RN(3557)
Descrição geral
The Human IL-1ra ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-1ra in serum, plasma, cell culture supernatants and urine.
Imunogênio
Recombinant Human IL-1 Receptor Antagonist
Aplicação
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Ações bioquímicas/fisiológicas
Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α and IL-1β by competitively binding to their type I and type II receptors. IL-1RA plays a vital role in inhibition of acute pro-inflammatory response and forbidding chronic inflammation from damaging healthy tissues. Abnormal expression of IL-1RA leads to development of inflammatory or autoimmune related diseases. Allelic polymorphism of IL-1RA leads to inflammatory bowel disease (IBD). Therapeutically, IL-1RA may help in the treatment of sepsis, rheumatoid arthritis, asthma. Overexpression of IL-1RA is observed in serum of psoriatic arthritis (PsA) patients.
Outras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Componentes do kit também disponíveis separadamente
Nº do produto
Descrição
SDS
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Met. Corr. 1
Código de classe de armazenamento
8A - Combustible corrosive hazardous materials
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Relationship of plasma leptin to plasma cytokines and human survivalin sepsis and septic shock.
Arnalich F
The Journal of Infectious Diseases, 180(3), 908-911 (1999)
A novel association between IL1-Ra (receptor antagonist) gene polymorphism and T1DM in Al-Madina Al-Mounawra.
Ali RA
European Review for Medical and Pharmacological Sciences, 19(19), 3701-3708 (2015)
Allelic polymorphism in IL-1 beta and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease.
Bioque G
Clinical and Experimental Immunology, 102(2), 379-383 (1995)
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist.
Bresnihan B
Arthritis and Rheumatism, 41(12), 2196-2204 (1998)
Serum levels of IL-10, IL-6, IL-1ra, and sIL-2R in patients with psoriatic arthritis.
Elkayam O
Rheumatology International, 19(3), 101-105 (2000)
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