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Merck
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Key Documents

RAB0082

Sigma-Aldrich

Human CD163 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reatividade de espécies

human

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable
capture ELISA: suitable

entrada

sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 30 pg/mL
standard curve range: 32.77-8000 pg/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... CD163(9332)

Descrição geral

The Human CD163 (also known as hemoglobin scavenger receptor) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD163 in serum, plasma, cell culture supernatants and urine.

Imunogênio

Recombinant Human CD163

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human CD163 ELISA kit has been used to measure the levels of CD163 in plasma samples and cell culture supernatants.

Ações bioquímicas/fisiológicas

Cluster of differentiation 163 (CD163) is a scavenger receptor. It is expressed on the surface of activated macrophages. This protein modulates anti-inflammatory functions and has a role in hemoglobin-haptoglobin clearance. Various cytokines influence the expression of CD163. It may be associated with hepatocellular carcinoma.

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible, corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Macrophage activation marker soluble CD163 may predict disease progression in hepatocellular carcinoma.
Kazankov K
Scandinavian Journal of Clinical and Laboratory Investigation (2016)
A Ross Eckard et al.
HIV medicine, 15(9), 537-546 (2014-03-22)
HIV-infected patients on antiretroviral therapy (ART) have an increased cardiovascular disease (CVD) risk as a result of heightened inflammation and immune activation, despite at times having normal lipids and few traditional risk factors. Biomarkers are needed to identify such patients
Clinical significance of soluble CD163 in polymyositis-related or dermatomyositis-related interstitial lung disease.
Enomoto Y
Arthritis Research & Therapy (2017)
Martin Hoenigl et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 69(4), 676-686 (2018-11-13)
Despite effective antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains associated with higher morbidity and mortality, driven, in part, by increased inflammation. Our objective was to identify associations between levels of plasma biomarkers of chronic inflammation, microbial translocation, and
Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke
Grant C
Scientific Reports (2017)

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