P2745
Protein Phosphatase Inhibitor 1 human
Sinônimo(s):
Inhibitor 1 human
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About This Item
Produtos recomendados
fonte biológica
human
Nível de qualidade
recombinante
expressed in E. coli
Ensaio
>95% (SDS-PAGE)
forma
solution
peso molecular
~31 kDa
apparent mol wt ~27 kDa
Condições de expedição
dry ice
temperatura de armazenamento
−70°C
Informações sobre genes
human ... PPP1R1A(5502) , PPP1R8(5511)
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Aplicação
This protein phosphatase inhibitor 1 is suitable for use as a substrate to identify novel phosphatases and kinases that modulate protein phosphatase inhibitor 1 activity. This product is also suitable for use in affinity pull-down binding studies. Protein Phosphatase Inhibitor 1 human has been used as a component in the sucrose cell lysis buffer. It has also been used for intraperitoneal injection of mice prior to natterins or saline treatment in pharmacological intervention studies.
Ações bioquímicas/fisiológicas
Intimately involved in glycogen metabolism as an inhibitor of phosphorylase phosphatase, the enzyme responsible for conversion of phosphorylase b to phosphorylase a. Inhibition is invoked only upon phosphorylation by a cAMP-dependent protein kinase.
forma física
Supplied as a solution in 50 mM Tris-HCl, pH 7.0, containing 0.1 mM PMSF, 14 mM 2-mercaptoethanol, and 10% glycerol
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Skin Sens. 1
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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