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N8133

Sigma-Aldrich

Nerve Growth Factor from Vipera lebetina venom

lyophilized powder, suitable for cell culture

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About This Item

Número CAS:
9061-61-4
Número MDL:
MFCD00147703
Código UNSPSC:
12352202
NACRES:
NA.77

product name

Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture

fonte biológica

Vipera Lebetina

Nível de qualidade

200

forma

lyophilized powder

potência

0.2-20 μg/mL ED50/EC50

qualidade

endotoxin tested

peso molecular

protein 32.5 kDa

embalagem

pkg of 0.1 mg

técnica(s)

cell culture | mammalian: suitable

Impurezas

<10 EU/vial

cor

white to off-white

nº de adesão UniProt

P25428

temperatura de armazenamento

−20°C

Categorias relacionadas

forma física

Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.

Nota de preparo

Isolated from the snake venom of V. lebetina.

Nota de análise

The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6098-6106 (2014-04-25)
Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the
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Journal of cellular physiology, 229(6), 783-790 (2013-10-30)
The peripheral application of the M2 cholinergic agonist arecaidine on sensory nerve endings shows anti-nociceptive properties. In this work, we analyze in vitro, the mechanisms downstream M2 receptor activation causing the analgesic effects, and in vivo the effects produced by
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Biochimica et biophysica acta, 1830(8), 4130-4136 (2013-04-16)
Neurotrophins are important regulators for neural development and regeneration. Nerve growth factor (NGF) therapy has been tested in various models of neural injury and degeneration. However, whether NGF can reach target tissues and maintain effective concentration for a certain period
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Trends in pharmacological sciences, 35(7), 338-348 (2014-06-26)
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