MAK058
D-Lactate Colorimetric Assay
sufficient for 100 colorimetric tests
Sinônimo(s):
D-Lactate Test Kit
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About This Item
Produtos recomendados
uso
sufficient for 100 colorimetric tests
aplicação(ões)
cosmetics
food and beverages
método de detecção
colorimetric
doença(s) relevante(s)
neurological disorders; gastrointestinal diseases
temperatura de armazenamento
−20°C
Descrição geral
D-Lactate, typically present in the bloodstream at nanomolar concentrations, is produced by an intestinal source or via the methylglyoxal pathway. In mammals, D-Lactate metabolism requires D-Lactate hydrogenase and is metabolized slowly, thus an increase in blood concentration levels can lead to acidemia and acidosis. The severity of this D-lactic acidosis can be associated with neurotoxic symptoms. Significant D-Lactate accumulations in the body can also be related to impaired metabolism and excretion.
Aplicação
D-Lactate Colorimetric Assay kit has been used to determine the stereospecificity of lactate produced.
Adequação
Suitable for use with samples of serum, plasma, cells, culture and fermentation media.
Princípio
In this assay, D-Lactate is specifically oxidized by D-Lactate hydrogenase and generates a proportional colorimetric product measured at 450 nm. The useful concentration range in samples is 0.1-10 mM D-Lactate.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Dam. 1 - Skin Corr. 1B
Código de classe de armazenamento
8A - Combustible corrosive hazardous materials
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